A person who likes taking care of others; helpful or eager to look after people (can sometimes imply meddlesome).
彼は世話好きで、いつも近所の子供たちの面倒を見ている。
He's the kind of helpful person who always looks after the neighborhood kids.
世話好きな性格は職場では重宝されることもある。
A helpful nature can sometimes be valued in the workplace.
彼女は世話好きが高じてボランティアを始めた。
Her love of helping others led her to start volunteering.