To take offense; to become angry; to get upset with someone or something.
彼は同僚の一言で簡単に腹を立てる。
He gets upset easily at a colleague's remark.
お願いを無視されたとき、彼女は腹を立てて帰ってしまった。
When her request was ignored, she got angry and left.
子どもがわがままを言うと父親は腹を立てることがある。
If a child acts selfishly, the father sometimes gets angry.
腹を立てる前に、まず話し合ってみよう。
Before getting angry, let's try to talk it over.