Medicines or drugs in general; depending on context, it can also refer to controlled or illegal drugs (e.g., narcotics).
薬物療法で症状が改善した。
Symptoms improved with drug therapy.
違法な薬物の密輸が摘発された。
The smuggling of illegal drugs was busted.
処方された薬物は用法を守って服用してください。
Please take the prescribed medicines according to the instructions.
薬物乱用は健康に重大な害を及ぼす。
Drug abuse causes serious harm to health.