1Spare time; free time or leisure.
週末はいとまがあるから、一緒に映画に行かない？
I'm free this weekend — want to go to a movie together?
子どもが昼寝している間にいとまができた。
I had some free time while the child was napping.
いとまがあれば、料理教室に通いたい。
If I had free time, I'd like to attend a cooking class.
2Time off; leave; vacation — taking time away from work or duties.
彼は家族の事情でしばらくいとまを取ることになった。
He decided to take time off for family reasons.
会社にいとまを願い出て、海外へ行った。
He requested leave from the company and went abroad.
3A dated/old-fashioned term meaning resignation, dismissal, or divorce.
彼は職を辞するいとまを上申した（文語的表現）。
He submitted his resignation (literary expression).
4Leaving; taking one's leave; farewell — the act of departing or saying goodbye (as in 'おいとま').
用事があるので、ここでいとまをいただきます。
I have something to do, so I'll take my leave here.
訪問先で丁寧にいとまを告げて帰った。
I politely took my leave at the place I visited and went home.