1A set expression of concern said to someone who is sick or injured, meaning 'please take care of yourself' or 'get well soon'; typically said at hospitals, pharmacies, or when parting.
診察が終わり、看護師さんに『お大事に』と言われた。
After the checkup, the nurse told me, 'Take care.'
風邪で休んでいる同僚に、メールで『お大事にしてください』と伝えた。
I emailed my colleague who's out sick with a cold, saying, 'Please take care of yourself.'
薬局で薬をもらうとき、『お大事にどうぞ』と声をかけられた。
When I picked up my medicine at the pharmacy, they said, 'Get well soon.'
怪我をしたと聞いて、『お大事にね』と声をかけた。
When I heard he'd been hurt, I told him, 'Get well soon.'