A rash or skin eruption caused by irritation (e.g., contact dermatitis). Often used in the verb form かぶれる (to develop a rash).
新しい洗剤で手がかぶれた。
My hands broke out in a rash from the new detergent.
金属に触れてかぶれが出たので皮膚科に行った。
I developed a rash from touching metal, so I went to a dermatologist.
かぶれがひどくて薬を塗っている。
The rash is bad, so I'm applying medicine.
Being strongly influenced by something (often with a critical nuance). Used as ～かぶれ to suggest superficial imitation or affectation.
彼はジャズかぶれで、いつも難しい話をしたがる。
He's fallen under the spell of jazz and always wants to talk about sophisticated topics.
昭和かぶれの店内は古いポスターだらけだった。
The Showa-era–obsessed shop was full of old posters.
彼女はフランスかぶれで、料理もフレンチばかり作る。
She's into all things French and cooks French food all the time.
Used in the ～かぶれ form to indicate being crazy about or affected by something, often with a teasing or slightly derogatory tone.
アニメかぶれの彼はコスプレが大好きだ。
He's an anime obsessive and loves cosplaying.
あの店は古着かぶれの若者でにぎわっている。
That shop is crowded with vintage-clothes–obsessed young people.