1A coarse, derogatory second-person pronoun meaning "you" (similar to お前); often used in angry or threatening speech, stereotypically masculine and rough.
てめえ、何をしてやがるんだ！
You bastard, what are you doing! (angry/threatening)
「てめえ、ふざけるんじゃねえ！」と彼は叫んだ。
"Don't mess with me, you!" he shouted.
漫画では悪役がよく『てめえ』を使う。
In manga villains often use 'てめえ.'
2In some historical, dialectal, or special uses it can refer to oneself or a third person; however, in modern colloquial speech it is mainly a derogatory 'you.'
てめえのことはてめえで何とかしろ。
Deal with your own problems yourself.
昔の文献では『てめえ』が一人称的に使われる例もある。
There are examples in old texts where 'てめえ' is used in a first-person way.