A superior or someone higher up in the workplace or organization; a boss or senior.
この件はまず上役に相談してから進めてください。
Please consult with your superior about this matter before proceeding.
上役の許可がないとプロジェクトを始められない。
You can't start the project without approval from a superior.
飲み会では上役にも気を使って話題を選んだ。
At the company party I was careful with topics because seniors were present.