A matter, affair, or item — something that has occurred or an issue to be dealt with; often used in slightly formal contexts.
会議では重要な事柄から順に議題を進めた。
In the meeting we proceeded with the agenda starting from the important matters.
その事柄について詳しく調べる必要がある。
We need to investigate that matter in detail.
彼の話は事柄を簡潔にまとめていた。
His talk summarized the matters concisely.