To take charge of or be responsible for a task or role (e.g., a class, project, or duty).
来学期は彼が3年生のクラスを受け持つことになった。
Next semester he will be in charge of a third-year class.
そのプロジェクトの進行役を私が受け持つ。
I'll take charge of coordinating that project's progress.
新入社員の教育は先輩が受け持つ予定だ。
A senior employee is scheduled to take charge of training the new hires.