The state of losing something; loss or forfeiture (of rights, feelings, belongings, etc.).
彼は交通事故で記憶を喪失した。
He lost his memory in a traffic accident.
利益の喪失は会社にとって大きな打撃だ。
Loss of profits is a big blow for the company.
自信を喪失すると行動が消極的になりがちだ。
When you lose confidence, your behavior tends to become passive.