To point to or indicate something (a place, object, direction, etc.), or to show/point out clearly often using gesture or explanation.
地図を指し示して、駅の場所を教えた。
I pointed to the map and showed where the station was.
先生は黒板のグラフを指し示して、傾向を説明した。
The teacher indicated the graph on the blackboard and explained the trend.
彼は証拠の写真を指し示して、無実を主張した。
He pointed to the photographic evidence and insisted he was innocent.