1Slanting, tilted, diagonal, or oblique — at an angle, neither horizontal nor vertical.
壁の絵が斜めになっているので直した。
The picture on the wall was crooked, so I straightened it.
斜め向かいにコンビニがある。
There's a convenience store diagonally across from here.
紙を斜めに切って三角形を作った。
I cut the paper diagonally to make a triangle.
帽子を斜めにかぶるのが彼のスタイルだ。
Wearing his hat at an angle is his signature style.
2An off-kilter mood or attitude — being in a bad mood, sulky, or having a skewed/distorted view of something.
部長は今日、機嫌が斜めのようだ。
The manager seems to be in a bad mood today.
彼女は褒められても何だか斜めな反応をした。
Even when praised, she reacted in a strangely sulky way.
そんなに物事を斜めに見ないで、素直に受け止めたほうがいい。
You shouldn't look at things with such a skewed view — it's better to accept them honestly.