Anyway; in any case; used to move to a conclusion or action regardless of other factors.
今日は疲れているから、とにかく早く帰って休もう。
I'm tired today, so anyway I'll go home early and rest.
意見は分かれたが、とにかく期限までに仕上げてください。
Opinions differed, but in any case finish it by the deadline.
予算はあまりないが、とにかくやってみよう。
We don't have much budget, but at least let's try it.
Setting something aside; used in structures like 'Xはとにかく〜' to mean 'regardless of X; putting X aside'.
値段はとにかく品質が大事だ。
Regardless of price, quality is important.
見た目はともかく、とにかく中身が重要だ。
Putting appearance aside, what's inside is what matters.
彼の過去はとにかく、今の仕事ぶりを見よう。
Setting his past aside, let's look at how he works now.
Used as an emphatic 'really/truly/certainly' to strengthen the speaker's statement (colloquial).
このレストランはとにかくおいしい。
This restaurant is really delicious.
彼はとにかく頼りになる人だ。
He's truly a dependable person.